Evidence mounts for the health benefits of PACs, and future innovations in quality and testing will improve efficacy while revealing other health benefits.
According to researchers writing in the Cochrane Database of Systematic Reviews, cranberry juice and cranberry supplements both can significantly reduce repeat urinary tract infections (UTIs) in women, children, and individuals. The meta-analysis is the most comprehensive to date on the matter, and is an update of previous reviews published in the journal.
An article in July issue of Nutraceuticals World Magazine summarizes the findings, which is an update of previous findings publsihed in the Cochrane Review. “Now that we have included 50 studies in the review, we now have more conclusive evidence to support the efficacy of cranberry preparations in reducing the risk of symptomatic urinary tract infections in women with recurrent UTIs, children, and in people with a susceptibility to UTI due to an intervention such as radiation therapy,” said Elisabeth Hodson, corresponding author of the study and honorary consultant pediatric nephrologist at the Children’s Hospital at Westmead in Sydney, Australia.
Across the 50 studies assessed, which involved 8,857 people, there were no significant differences in whether cranberries were taken in the form of juice, tablets, or capsules.
Of the 50 studies, 45 studies compared cranberry products to either a placebo or no specific treatment. Twenty-six of the 45 studies could be analyzed for outcomes related to symptomatic, culture-verified UTIs.
Outcomes involving a total pool of 6,211 participants yielded moderately-certain evidence that cranberry products reduced UTI risk in women, children, and people who had interventions leaving them susceptible to UTIs.
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